In vitro electrophysiology

Donna Hammond

Donna L. Hammond, PhD

Title/Position
Professor, Carver Chair in Neuroscience IV
This laboratory is interested in the neuroanatomy, neurophysiology and neuropharmacology of the central nervous system (CNS) pathways that convey pain, as well as the bulbospinal pathways that mediate the production of analgesia. Our studies emphasize a systems-level approach in which many different...
chris-benson

Christopher Benson, MD

Title/Position
Professor
Dr. Benson's research interests include the study of ion channels involved in sensation. We have focused on a class of ion channels called Acid-sensing Ion Channels (ASICs), which play a role in responses to nociceptive, taste, and mechanical stimuli. We have discovered that ASICs are highly...
George Richerson

George B. Richerson, MD, PhD

Title/Position
Professor
Head, Neurology
We are studying the role of serotonin neurons in mediating the effects of acidosis on brain function and behavior. We have shown that serotonin neurons are exquisitely sensitive to changes in pH. They are close to large arteries in the brain and contribute to the increase in breathing induced by...
Marcinkiewcz, Catherine

Catherine Marcinkiewcz, PhD

Title/Position
Assistant Professor
Serotonin neurons are mainly localized to the raphe nuclei of the brainstem, but their axons are widely distributed throughout the nervous system and have a ubiquitous role in physiological processes and behavior. Adding to this complexity is the diverse array of high-affinity receptors that bind...
KayA

Alan R. Kay, PhD

Title/Position
Professor
A high concentration of free ionic zinc in synaptic vesicles is a prominent feature of some of the excitatory pathways in the mammalian forebrain. Despite the wealth of information on its distribution, and role in metalloenzymes and proteins, the role of vesicular zinc remains enigmatic, and serves...
Huxing Cui

Huxing Cui, PhD

Title/Position
Assistant Professor
We study the neural circuits and intraneuronal signaling mechanisms that regulate appetite, body weight, sleep, and cardiorespiratory function in mice and aim to understand how these regulatory processes go awry in metabolic disorders. To this end, we employee state-of-the-art neuroscience...
John Wemmie

John Wemmie, MD, PhD

Title/Position
Professor
My lab uses genetic manipulation in mice to study the effects of Acid Sensing Ion Channels (ASICs) on behavior. Because one of these channels, ASIC1, is abundant in the amygdala complex, we tested whether it plays a role in Pavlovian fear conditioning. We found that ASIC1a knockout mice have reduced...
Joseph Glykys

Joseph Glykys, MD, PhD

Title/Position
Assistant Professor
The Glykys Lab focuses on neuronal swelling (cytotoxic edema) and the inhibitory system. Our research's long-term goal is to better treat neuronal swelling and seizures, especially during the neonatal period. Our areas of research include: studying changes in neuronal chloride concentration and...
Mark Chapleau

Mark W. Chapleau, PhD

Title/Position
Professor
Dr. Chapleau's research focuses on neural mechanisms in cardiovascular regulation; with emphasis on baroreceptor mechanosensory transduction, modulation of excitability of baroreceptor and sympathetic neurons, and determinants of baroreflex sensitivity, arterial chemoreceptor reflex sensitivity and...
YoungS

Samuel M. Young, PhD

Title/Position
Associate Professor
My laboratory is focused on the fundamental question– “How do synapses enable neuronal circuits to transmit a wide diversity of information?” Outcomes from our work will define the molecular principles that govern how synaptic properties drive neuronal circuit output which underpins organism...