Christopher Benson, MD
Current Positions
- Professor of Internal Medicine-Cardiovascular Medicine
- Professor of Neuroscience and Pharmacology
- Clinical Director, Division of Cardiovascular Medicine
Education
- MD, University of Minnesota School of Medicine, Minneapolis, Minnesota
- Resident, Internal Medicine, University of Minnesota, Minneapolis, Minnesota
- Fellow, Cardiovascular Medicine, Oregon Health Sciences University, Portland, Oregon
Graduate Program Affiliations
Center, Program and Institute Affiliations
Licenses & Certifications
- Medical License, Iowa Board of Medicine
- Certification, American Board of Internal Medicine
- Certification, American Board of Internal Medicine, Cardiovascular Disease
Research Interests
Dr. Benson's research interests include the study of ion channels involved in sensation. We have focused on a class of ion channels called Acid-sensing Ion Channels (ASICs), which play a role in responses to nociceptive, taste, and mechanical stimuli. We have discovered that ASICs are highly expressed in cardiac sensory neurons and we believe they are particularly important as pH sensors in the setting of myocardial ischemia. In addition, we are interested in how cardiac afferent activation might trigger deleterious neural reflexes in cardiac disease states. Our lab is also interested on the general physiology of ASIC channels, and has discovered several proteins and signaling pathways that modulate ASIC function. Our research methods utilize electrophysiology, whole animal recordings, molecular and cell biology, and protein biochemistry techniques.
- Cellular and molecular neuroscience
- Systems neuroscience
- Behavioral neuroscience
- Ion channels
- Cardiovascular disorders
- Sensory systems
- Autonomic Nervous System
- Pain
- Animal behavior
- In vitro electrophysiology
- Molecular biology
- Cell culturing