We study the neural circuits and intraneuronal signaling mechanisms that regulate appetite, body weight, sleep, and cardiorespiratory function in mice and aim to understand how these regulatory processes go awry in metabolic disorders. To this end, we employee state-of-the-art neuroscience techniques, such chemogenetics, optogenetics, in vivo fiber photometry and electrophysiology, in various transgenic mouse models coupled with sophisticated physiological measurements, including wireless recording of EEG/EMG for sleep architecture analysis, indirect colorimetry for energy metabolism, whole body plethysmography for breathing patterns, and radiotelemetry recording of blood pressure in conscious mice.

Recent publications