Gene regulation

Marcinkiewcz, Catherine

Catherine Marcinkiewcz, PhD

Title/Position
Assistant Professor
Serotonin neurons are mainly localized to the raphe nuclei of the brainstem, but their axons are widely distributed throughout the nervous system and have a ubiquitous role in physiological processes and behavior. Adding to this complexity is the diverse array of high-affinity receptors that bind...
FrankCA

C. Andrew Frank, PhD

Title/Position
Associate Professor
Homeostasis is a robust form of regulation that allows a system to maintain a constant output despite external perturbations. In the nervous system, homeostasis plays a critical role in regulating neuronal and synaptic activity. Yet the molecular basis of this form of neural plasticity is generally...
RussoA

Andrew F. Russo, PhD

Title/Position
Professor
My research interest is the molecular basis of migraine. A hallmark of migraine is altered sensory perception coupled with head pain. To understand the mechanisms underlying these events, we have focused on the neuropeptide calcitonin gene-related peptide (CGRP), whose levels are elevated during...
Bassuk-Alexander

Alexander Bassuk, MD, PhD

Title/Position
Professor & Chair
Dr. Alex Bassuk is a Professor and Chair of Pediatrics, and holds the Joel and Jay Stead Chair for Leadership in Children's Medicine, and is Physician-in-Chief for University of Iowa Stead Family Children's Hospital. Dr. Bassuk is a member of the University of Iowa Graduate Programs in Genetics...
Hans-Joachim Lehmler

Hans-Joachim Lehmler, PhD

Title/Position
Professer
My laboratory is interested in the effect of environmental pollutants, such as neurotoxic polychlorinated biphenyls (PCBs), and their transformation products on the developing brain. We use exposomics approaches to identify the metabolites formed in various model systems, including animal models...
Huxing Cui

Huxing Cui, PhD

Title/Position
Assistant Professor
We study the neural circuits and intraneuronal signaling mechanisms that regulate appetite, body weight, sleep, and cardiorespiratory function in mice and aim to understand how these regulatory processes go awry in metabolic disorders. To this end, we employee state-of-the-art neuroscience...
SabharwalRasna

Rasna Sabharwal, PhD

Title/Position
Assistant Professor
My research focuses on elucidating central brain mechanisms underlying Alzheimer’s disease, psychosocial disorders, heart failure and sudden cardiac death. The lab uses multidisciplinary approaches including radiotelemetry, optogenetics, neurophysiology, pharmacology, behavioral and molecular...
LuoJia

Jia Luo, PhD

Title/Position
Professor; Pathology Endowed Chair in Alcohol Research
Alcoholism, alcohol abuse, and the medical complications of excessive drinking are major world-wide health problems. There are three long-term goals of my laboratory: (1) Alcohol exposure during development results in fetal alcohol spectrum disorders (FASD) and induces profound damages to the...
Jon Resch

Jon Resch, PhD

Title/Position
Assistant Professor
We aim to uncover the neural mechanisms underlying the homeostatic regulation of appetite and cardiometabolic physiology. To do so, we use genetically engineered mouse models and Cre-dependent AAVs to specifically map neuronal circuits as well as manipulate and record their activity in order to...
Joshua Weiner

Joshua Weiner, PhD

Title/Position
Professor
The mammalian brain is the most complex system in all of biology. The human brain has ~100 billion neurons and perhaps 500 trillion synapses, contact sites between neurons through which information flows. The differentiation of a vast array of distinct neuronal cell types from stem cell progenitors...