Current Positions

• Assistant Professor of Internal Medicine-Cardiovascular Medicine
• Assistant Professor of Neuroscience and Pharmacology

Education

• Research Fellow, Internal Medicine, University of Iowa, Iowa City, Iowa
• PhD, Physiology, University of Birmingham, Birmingham, United Kingdom

Graduate Program Affiliations

• Biomedical Science (Pharmacology)
• Biomedical Science (Molecular Medicine)
• Neuroscience

Center, Program and Institute Affiliations

• Cardiovascular Research Center
• Fraternal Order of Eagles Diabetes Research Center
• Iowa Neuroscience Institute

Research Interests

My research focuses on neurohumoral control of circulation in health, disease and aging.  Our goal is to identify therapies that can be translated to yield better clinical outcomes in cardiomyopathy, heart failure, hypertension, Alzheimer’s disease and amyotrophic lateral sclerosis.  Ongoing studies involve the renin-angiotensin system, sympathetic nervous system, and hypothalamic-pituitary adrenal axis. Expertise in my laboratory includes a combination of integrative cardiovascular, neurophysiological and autonomic approaches in genetically modified mice, such as in vivo radiotelemetry, optogenetics, electrophysiology, microdialysis and cardiac function assessment.  Our projects also incorporate molecular and cellular techniques, including siRNA and viral microinjections, RNAseq, immunohistochemistry and in situ hybridization.

Recent publications