Alzheimer's Disease

TranelD

Daniel T. Tranel, PhD

Title/Position
Professor
Neuroscience Ph.D. Program Director
My research is aimed at understanding brain-behavior relationships in humans, at systems level. Two main approaches are used: the lesion method, in which brain-damaged patients are studied with neuropsychological procedures to determine how certain lesion sites are related to certain cognitive and...
Marcinkiewcz, Catherine

Catherine Marcinkiewcz, PhD

Title/Position
Assistant Professor
Serotonin neurons are mainly localized to the raphe nuclei of the brainstem, but their axons are widely distributed throughout the nervous system and have a ubiquitous role in physiological processes and behavior. Adding to this complexity is the diverse array of high-affinity receptors that bind...
Georgina Aldridge

Georgina Aldridge, MD, PhD

Title/Position
Assistant Professor
In patient with lewy body disease, the protein alpha-synuclein aggregates, leading to severe multi-system symptoms, including hallucinations, loss of smell, dementia, imbalance, fluctuating confusion, and anxiety/depression. The main research goal of the Aldridge Laboratory is to understand the...
Gordon Buchanan

Gordon Buchanan, MD, PhD

Title/Position
Associate Professor
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in patients with intractable epilepsy, but specific mechanisms of how a seizure can cause death are poorly understood. Research efforts in my laboratory are focused on using animal models to understand the mechanisms by which...
KayA

Alan R. Kay, PhD

Title/Position
Professor
A high concentration of free ionic zinc in synaptic vesicles is a prominent feature of some of the excitatory pathways in the mammalian forebrain. Despite the wealth of information on its distribution, and role in metalloenzymes and proteins, the role of vesicular zinc remains enigmatic, and serves...
Hans-Joachim Lehmler

Hans-Joachim Lehmler, PhD

Title/Position
Professer
My laboratory is interested in the effect of environmental pollutants, such as neurotoxic polychlorinated biphenyls (PCBs), and their transformation products on the developing brain. We use exposomics approaches to identify the metabolites formed in various model systems, including animal models...
SabharwalRasna

Rasna Sabharwal, PhD

Title/Position
Assistant Professor
My research focuses on elucidating central brain mechanisms underlying Alzheimer’s disease, psychosocial disorders, heart failure and sudden cardiac death. The lab uses multidisciplinary approaches including radiotelemetry, optogenetics, neurophysiology, pharmacology, behavioral and molecular...
Joel Geerling

Joel C. Geerling, MD, PhD

Title/Position
Assistant Professor
In the lab, we use genetic techniques to isolate and manipulate neurons that mediate basic physiologic functions including sleep, appetite, bladder control, and thermoregulation. My focus lies in identifying and deciphering previously unknown connections between neurons in the brainstem and other...
Marco Hefti

Marco M. Hefti, MD

Title/Position
Assistant Professor
I am interested in the role of the tau protein in human brain development and in response to early-life hypoxic-ischemic injury, and in how this related to the development of age-related tauopathies such as Alzheimers disease. Recent publications
Matthew Potthoff

Matthew Potthoff, PhD

Title/Position
Associate Professor
My research program is focused on two strategically developed areas of research. The first is exploring how energy and glucose homeostasis is regulated by novel endocrine pathways. More specifically, we examine how endocrine signals in the periphery communicate with the central nervous system...