My research focuses on identifying and characterizing novel genetic and molecular mechanisms of prevalent diseases, including neurological, cardiovascular and metabolic conditions. Specific research topics include: 1) Effects of microRNAs / RNA-binding proteins in neurological (Parkinson's and Alzheimer's) and cardiac disease (heart failure and arrhythmias), 2) Viral and non-viral mediated inhibition of endogenous microRNAs for neuro- and cardio-protection, 3) Discovering and characterizing new or understudied disease-related genes and microproteins in brain and heart, 4) Gene-targeted therapies for brain and heart disease, and 5) Regulation of mitochondrial metabolism / function.