Georgina Aldridge, MD, PhD

Assistant Professor

In patient with lewy body disease, the protein alpha-synuclein aggregates, leading to severe multi-system symptoms, including hallucinations, loss of smell, dementia, imbalance, fluctuating confusion, and anxiety/depression. The main research goal of the Aldridge Laboratory is to understand the roles that synuclein pathology and protein misfolding in the cortex play in the development of these symptoms.

Dr. Aldridge and her team use 2-photon microscopy to image neuronal structure (dendritic spines, dendrites, and axons) and function (calcium imaging) over time in living mice to evaluate how alpha-synuclein and other proteins involved in neurodegenerative conditions lead to changes in cortical function.

Recent publications

Research areas
  • Systems neuroscience
  • Behavioral neuroscience
  • Neuroanatomy
  • Clinical neuroscience
  • Alzheimer's Disease
  • Neurodegenerative disorders
  • Parkinson's Disease
  • Psychiatric disorders
  • Frontal cortex
  • Brainstem
  • Learning
  • Memory
  • Timing
  • Neuroimaging
  • Animal behavior
  • 2-photon
Georgina Aldridge

5334 PBDB
United States

Phone Number