Molecular biology

John Manak

John Manak, PhD

Title/Position
Professor
One of the primary areas of research in my laboratory is elucidating the genetic basis of neurological disorders, including epilepsy, Alzheimer’s Disease, and neurodevelopmental disorders. We have found that mutations in the prickle gene cause seizure disorders in fruit flies, similar to those...
Jon Resch

Jon Resch, PhD

Title/Position
Assistant Professor
We aim to uncover the neural mechanisms underlying the homeostatic regulation of appetite and cardiometabolic physiology. To do so, we use genetically engineered mouse models and Cre-dependent AAVs to specifically map neuronal circuits as well as manipulate and record their activity in order to...
Joshua Weiner

Joshua Weiner, PhD

Title/Position
Professor
The mammalian brain is the most complex system in all of biology. The human brain has ~100 billion neurons and perhaps 500 trillion synapses, contact sites between neurons through which information flows. The differentiation of a vast array of distinct neuronal cell types from stem cell progenitors...
Kamal Rahmouni.

Kamal Rahmouni, PhD

Title/Position
Professor
The work in my laboratory is focused on the neurobiology of metabolism, energy homeostasis and cardiovascular function and related disorders such as obesity, diabetes and hypertension. The central nervous system is a major player in the regulation of energy homeostasis as well as cardiovascular...
Kathleen Sluka

Kathleen A. Sluka, PT, PhD

Title/Position
Professor
Dr. Sluka's laboratory studies the peripheral and central mechanisms of chronic musculoskeletal pain. These studies primarily involve the use of animal models of muscle pain developed and characterized in Dr. Sluka's laboratory. Current projects are aimed at deciphering the role of descending...
Mark Chapleau

Mark W. Chapleau, PhD

Title/Position
Professor
Dr. Chapleau's research focuses on neural mechanisms in cardiovascular regulation; with emphasis on baroreceptor mechanosensory transduction, modulation of excitability of baroreceptor and sympathetic neurons, and determinants of baroreflex sensitivity, arterial chemoreceptor reflex sensitivity and...
Matthew Potthoff

Matthew Potthoff, PhD

Title/Position
Associate Professor
My research program is focused on two strategically developed areas of research. The first is exploring how energy and glucose homeostasis is regulated by novel endocrine pathways. More specifically, we examine how endocrine signals in the periphery communicate with the central nervous system...
Michael Anderson

Michael Anderson, PhD

Title/Position
Professor
Research in my laboratory is aimed at understanding fundamental physiological properties of the eye and the pathophysiological mechanisms underlying a variety of complex eye diseases. Of primary interest are the glaucomas, a leading cause of blindness that affects approximately 70 million people...
Peter Thorne

Peter Thorne, PhD

Title/Position
Professor
My research group studies inhaled environmental and occupational pollutants and engineered nanomaterials to understand mechanisms of their toxicity to the lung as well as the immune, neurological, and endocrine systems. We characterize toxicity in a manner that allows us to translate research...
YoungS

Samuel M. Young, PhD

Title/Position
Associate Professor
My laboratory is focused on the fundamental question– “How do synapses enable neuronal circuits to transmit a wide diversity of information?” Outcomes from our work will define the molecular principles that govern how synaptic properties drive neuronal circuit output which underpins organism...