Photoreceptor organization, signaling, and disease.

The Baker lab is interested is all aspects of photoreceptor cell and molecular biology. We have made discoveries related to protein trafficking and degradation, synapse development, and the integration of signaling between rod and cone photoreceptors which are used in dim or bright light respectively. Current work is focused on a form of inherited childhood blindness that is caused by the loss of a potassium channel that helps control the electrical response of photoreceptors in different lighting conditions. Please see the Baker Lab webpage for more information.