My lab focuses on the topic of brain growth and development in the pediatric CKD population. Specifically, our current work includes an NIDDK R01-funded project utilizing magnetic resonance imaging (MRI) to quantitatively characterize the structure of the brain (e.g., volumes of regions and tissues) in mild to moderate pediatric CKD prior to need for dialysis or transplant. In conjunction with standardized neurocognitive testing, specialized neuroimaging measures are used to evaluate brain structure, function, and metabolism in this population, as well as to understand the relationship to underlying renal disease.