Dr. Chapleau's research focuses on neural mechanisms in cardiovascular regulation; with emphasis on baroreceptor mechanosensory transduction, modulation of excitability of baroreceptor and sympathetic neurons, and determinants of baroreflex sensitivity, arterial chemoreceptor reflex sensitivity and sympathovagal balance in health and disease. Studies explore mechanisms of dysregulation and use of novel therapeutic approaches (e.g., gene transfer, vagus nerve stimulation, exercise, electroacupuncture) in mouse models of hypertension, heart failure, hypertrophic cardiomyopathy and metabolic syndrome.

Recent publications