Immunofluorescence microscopy


C. Andrew Frank, PhD

Associate Professor
Homeostasis is a robust form of regulation that allows a system to maintain a constant output despite external perturbations. In the nervous system, homeostasis plays a critical role in regulating neuronal and synaptic activity. Yet the molecular basis of this form of neural plasticity is generally...

Steven H. Green, PhD

We study the molecular and cellular mechanisms by which neuronal survival and synaptogenesis are regulated by neural activity. For studies of survival, we principally use spiral ganglion neurons (SGNs) in the cochlea. SGNs are dependent on their presynaptic input, the hair cells, for their survival...