Current Positions

• Associate Professor of Molecular Physiology and Biophysics

Education

• BS in Biology, Minor: Chemistry, University of Nevada, Las Vegas, Nevada
• PhD in Molecular and Cellular Biology, University of Washington, Seattle, Washington
• Fellow, Howard Hughes
• Postdoctoral Fellow, University of Washington
• Postdoctoral Fellow, United Negro College
• Postdoctoral Fellow in Molecular Biotechnology, Department of Molecular Biotechnology and Institutes for Systems Biology, Seattle, Washington, United States

Graduate Program Affiliations

• Biomedical Science (Cancer Biology)
• Biomedical Science (Molecular Physiology and Biophysics)
• Medical Scientist Training Program

Research Interests

My laboratory utilizes quantitative mass spectrometry to study signal transduction pathways in normal and diseased cells. We are studying how perturbations in androgen receptor signaling impacts disease progression in human prostate cancer. Our long-term goals are to build quantitative models of androgen-regulated signaling pathways in prostate cancer. We will use these models to understand the evolution and progression of hormone-refractory prostate cancers. We anticipate our findings will define new biomarkers of diagnostic, prognostic, or therapeutic value to patients afflicted by life-threatening hormone-refractory prostate cancers.

• Functional analyses of androgen-sensitive post-translationally modified networks involved in AR-mediated transcription
• Studying Androgen-related Disease Signaling Pathways using Directed and Targeted Proteomic Workflows
• Functional analyses of the AR-interacting protein complexes
• Protein Biomarkers: Validation of Prognostic Biomarkers in Human Prostate Cancer
• Functional analyses of androgen-sensitive coregulators of AR-mediated transcription
• Androgen Signaling Networks in Human Prostate Cancer
• Subcellular mapping of androgen-sensitive protein complexes involved in AR-mediated transcription