Janice Staber, MD
Associate Professor
Department
Pediatrics
Biography
Current Positions
- Associate Professor of Pediatrics - Hematology/Oncology
Education
- Resident in Pediatrics, University of Iowa Children's Hospital, Iowa City, Iowa
- MD in Medicine, University of Iowa, Iowa City, Iowa
- Fellow in Pediatrics, Hematology/Oncology, University of Iowa Children's Hospital, Iowa City, Iowa
- BS in Biochemistry, with Honors, University of Iowa, Iowa City, Iowa
- Fellow in Pediatric Hematology/Oncology, University of Iowa Children's Hospital, Iowa City, Iowa
Graduate Program Affiliations
Center, Program and Institute Affiliations
Licenses & Certifications
- American Board of Pediatrics
- Certificate, Diagnosis and Management of Coagulation Disorders, Resident and Fellowship Workshop, Cincinnati, OH
- Permanent Iowa Medical License
- American Board of Pediatric Hematology/Oncology
- Resident Iowa Medical License
Research Interests
My research focuses on three key knowledge gaps in hemophilia: 1) mechanisms leading to decreased brain volumes in hemophilia A, 2) defining the executive dysfunction and behavior changes in hemophilia A, and 3) neuroinflammatory biomarkers to predict changes in the brain. My research laboratory studies the effect of cerebral microbleeds and neuroinflammation on brain structure and behavior changes in hemophilia A mouse model. We utilize piggyBac-mediated gene therapy in mice to determine if we can correct these changes. Simultaneously with my work in the hemophilia A mouse model, I conduct studies in patients with hemophilia given the lack of data in human subjects on brain structure and neurocognition.
Research areas
- Cellular and molecular neuroscience
- Cognitive neuroscience
- Behavioral neuroscience
- Neuroanatomy
- Clinical neuroscience
- Hormones
- Neuroinflammation
- Psychiatric disorders
- Bleeding disorders
- Hippocampus
- Cerebellum
- Neuroimaging
- Animal behavior
- Molecular biology