Janice Staber, MD

Associate Professor

My research focuses on three key knowledge gaps in hemophilia: 1) mechanisms leading to decreased brain volumes in hemophilia A, 2) defining the executive dysfunction and behavior changes in hemophilia A, and 3) neuroinflammatory biomarkers to predict changes in the brain. My research laboratory studies the effect of cerebral microbleeds and neuroinflammation on brain structure and behavior changes in hemophilia A mouse model. We utilize piggyBac-mediated gene therapy in mice to determine if we can correct these changes. Simultaneously with my work in the hemophilia A mouse model, I conduct studies in patients with hemophilia given the lack of data in human subjects on brain structure and neurocognition.


Recent publications

Research areas
  • Cellular and molecular neuroscience
  • Cognitive neuroscience
  • Behavioral neuroscience
  • Neuroanatomy
  • Clinical neuroscience
  • Hormones
  • Neuroinflammation
  • Psychiatric disorders
  • Bleeding disorders
  • Hippocampus
  • Cerebellum
  • Neuroimaging
  • Animal behavior
  • Molecular biology
Staber, Janice.jpg

3080 ML
United States

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