Gloria Lee, Ph.D.

Gloria Lee, PhD
Internal Medicine
Research focus: 

Neuronal cytoskeleton, signal transduction, and neurodegenerative diseases


B191 ML

Our laboratory studies tau protein, a microtubule associated protein that is also the primary component of the neurofibrillary tangles of Alzheimer's disease. A few years ago, we discovered that tau interacts with non-receptor src family tyrosine kinases. We are currently identifying and investigating new functions acquired by tau as a consequence of this interaction. Our hypothesis is that tau has a role in signal transduction in neurons. We are also investigating a possible role for this interaction in the neuropathogenesis of Alzheimer's disease and other age-related neurodegenerative diseases.

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